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Invitrogen™ EIF4A1/EIF4A2/EIF4A3 Polyclonal Antibody
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Product Code. 17209453 Shop All Thermo Scientific Products
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100 μL
Unit Size:
100µL
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17209453 100 μL 100µL
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Product Code. 17209453 Supplier Invitrogen™ Supplier No. PA5116950

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Description

Rabbit Polyclonal Antibody

Positive Samples: 293T, HeLa, HepG2, MCF7, C2C12, Mouse brain, Rat brain Immunogen sequence: MSASQDSRSR DNGPDGMEPE GVIESNWNEI VDSFDDMNLS ESLLRGIYAY GFEKPSAIQQ RAILPCIKGY DVIAQAQSGT GKTATFAISI LQQIELDLKA.

The eIF4A proteins are involved in many aspects of RNA metabolism due to their RNA-binding capacity and ATPase activity. eIF4A1 and eIF4A2 are cytoplasmic, whereas eIF4A3 is nuclear-localized. In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon.
TRUSTED_SUSTAINABILITY

Specifications

Antigen EIF4A1/EIF4A2/EIF4A3
Applications ELISA, Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1.638 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.05% ProClin 300; pH 7.3
Gene EIF4A3
Gene Accession No. P10630, P38919, P60842, P60843, Q14240, Q3B8Q2, Q5RKI1, Q91VC3
Gene Alias 2400003O03Rik; 4833432N07Rik; ATP-dependent RNA helicase DDX48; ATP-dependent RNA helicase eIF4A-1; ATP-dependent RNA helicase eIF4A-2; ATP-dependent RNA helicase eIF4A-3; BM-010; Ddx2a; Ddx2b; Ddx48; DEAD (Asp-Glu-Ala-Asp) box polypeptide 48; DEAD box protein 48; Eif4; EIF4A; EIF-4A; EIF4A1; EIF4A2; Eif4a3; eIF-4A-I; eIF4A-I; eIF-4A-II; eIF4A-II; eIF4AIII; eIF-4A-III; eIF4A-III; EIF4F; eukaryotic initiation factor 4AI; Eukaryotic initiation factor 4A-I; eukaryotic initiation factor 4A-II; Eukaryotic initiation factor 4A-III; Eukaryotic initiation factor 4A-III, N-terminally processed; Eukaryotic initiation factor 4A-like NUK-34; Eukaryotic translation initiation factor 4A isoform 3; eukaryotic translation initiation factor 4A, isoform 1; eukaryotic translation initiation factor 4A, isoform 2; eukaryotic translation initiation factor 4A, isoform 3; eukaryotic translation initiation factor 4A1; eukaryotic translation initiation factor 4A2; eukaryotic translation initiation factor 4A3; hNMP 265; initiation factor eIF-4A long form; KIAA0111; mKIAA0111; MUK34; NMP 265; NMP265; Nuclear matrix protein 265; NUK34; protein synthesis initiation factor 4AII; RCPS
Gene Symbols EIF4A1, EIF4A2, EIF4A3
Host Species Rabbit
Immunogen A synthetic peptide corresponding to a sequence within amino acids 1-100 of human eIF4A (NP_0014071).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 13681, 13682, 192170, 1973, 1974, 287436, 303831, 688288, 9775
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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