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Invitrogen™ eIF2b gamma Monoclonal Antibody (1H3)

Description
MA1-078 detects eIF2B3 in human, non-human primate and rat samples and has been successfully used in Western blot, ICC/IF, IHC (P) and immunoprecipitation applications. The immunogen for MA1-078 is full length human eIF2B3 produced in HEK293T cells.
EIF2B3 catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP. Mutations in each of the five subunits of translation initiation factor eIF2B, including subunit 3, can cause leukoencephalopathy with vanishing white matter. EIF2B3 has also been identified as a cofactor of hepatitis C virus internal ribosome entry site-mediated translation.
Specifications
Specifications
| Antigen | eIF2b gamma |
| Applications | Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot, RNA Immunoprecipitation, Immunocytochemistry |
| Classification | Monoclonal |
| Clone | 1H3 |
| Concentration | 1 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 1mg/mL BSA, 30% glycerol and 0.05% sodium azide |
| Gene | EIF2B3 |
| Gene Accession No. | P70541, Q9NR50 |
| Gene Alias | 1190002P15Rik; EIF-2B; eIF-2B GDP-GTP exchange factor subunit gamma; EIF2B3; Eif2bg; EIF2Bgamma; eukaryotic translation initiation factor 2B subunit gamma; eukaryotic translation initiation factor 2B, subunit 3; eukaryotic translation initiation factor 2B, subunit 3 (gamma, 58kD); eukaryotic translation initiation factor 2B, subunit 3 gamma; eukaryotic translation initiation factor 2B, subunit 3 gamma, 58kDa; translation initiation factor eIF-2B subunit gamma; Translation initiation factor eIF-2B subunit gamma-like protein |
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