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Invitrogen™ E2F2 Polyclonal Antibody
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Product Code. 15574822
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Quantity:
100 μL
Unit Size:
100µL
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15574822 100 μL 100µL
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Product Code. 15574822 Supplier Invitrogen™ Supplier No. PA541473

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Description

Rabbit Polyclonal Antibody

Peptide sequence: DQFLSPTLAC SSPLISFSPS LDQDDYLWGL EAGEGISDLF DSYDLGDLLI Sequence homology: Cow: 92%; Dog: 100%; Guinea Pig: 91%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 75%.

E2F2 is a member of the E2Ffamily of transcription factors. The E2F family plays a crucialrole in the control of cell cycle and action of tumor suppressorproteins and is also a target of the transforming proteins of smallDNA tumor viruses. The E2F proteins contain several evolutionallyconserved domains found in most members of the family. Thesedomains include a DNA binding domain, a dimerization domain whichdetermines interaction with the differentiation regulatedtranscription factor proteins (DP), a transactivation domainenriched in acidic amino acids, and a tumor suppressor proteinassociation domain which is embedded within the transactivationdomain. This protein and another 2 members, E2F1 and E2F3, have anadditional cyclin binding domain. This protein binds specificallyto retinoblastoma protein pRB in a cell-cycle dependent manner, andit exhibits overall 46% amino acid identity to E2F1.
TRUSTED_SUSTAINABILITY

Specifications

Antigen E2F2
Applications Immunohistochemistry, Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 2% sucrose and 0.09% sodium azide
Gene E2F2
Gene Accession No. P56931, Q14209
Gene Alias E2F transcription factor 2; E2F2; E2F-2; LOW QUALITY PROTEIN: transcription factor E2F2; transcription factor E2F2
Gene Symbols E2F2
Host Species Rabbit
Immunogen Synthetic peptide directed towards the middle region of human E2F2.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1870, 242705
Target Species Human, Mouse
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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