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Invitrogen™ Dynactin 2 Polyclonal Antibody
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Product Code. 16598931
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Quantity:
100 μL
Unit Size:
100µL
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16598931 100 μL 100µL
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Product Code. 16598931 Supplier Invitrogen™ Supplier No. PA596095

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Description

Rabbit Polyclonal Antibody

Immunogen sequence: HIIVNPNAAY DKFKDKRVGT KGLDFSDRIG KTKRTGYESG EYEMLGEGLG VKETPQQKYQ RLLHEVQELT TEVEKIKTTV KESATEEKLT PVLLAKQLAA LKQQLVASHL EKLLGPDAAI NLTDPDGALA KRLLLQLEAT KNSKGGSGGK TTGTPPDSSL VTYELHSRPE QDKFSQAAKV AELEKRLTEL ETAVRCDQDA QNPLSAGLQG ACLMETVELL QAKVSALDLA VLDQVEARLQ SVLGKVNEIA KHKASVEDAD TQSKVHQLYE T; Positive Samples: MCF7; Cellular Location: Cytoplasm, Membrane, Peripheral membrane protein, centrosome, cytoskeleton, microtubule organizing center.

This gene encodes a 50-kD subunit of dynactin, a macromolecular complex consisting of 10-11 subunits ranging in size from 22 to 150 kDa. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit is present in 4-5 copies per dynactin molecule. It contains three short alpha-helical coiled-coil domains that may mediate association with self or other dynactin subunits. It may interact directly with the largest subunit (p150) of dynactin and may affix p150 in place.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Dynactin 2
Applications ELISA, Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.55 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene DCTN2
Gene Accession No. Q13561, Q6AYH5
Gene Alias 2310042E05Rik; 50 kDa dynein-associated polypeptide; C130077D06Rik; C87049; DCTN2; dctn2 protein; DCTN50; DCTN-50; dynactin 2; dynactin 2 (p50); dynactin complex 50 kDa subunit; Dynactin subunit 2; dynamitin; epididymis secretory protein Li 77; GMP23-48K; Growth cone membrane protein 23-48K; HEL-S-77; hypothetical protein LOC527201; p50; p50 dynamitin; p50/dynamitin; RBP50; zgc:63867
Gene Symbols DCTN2
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 50-320 of human DCTN2 (NP_0063911).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10540, 299850
Target Species Human, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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