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Dxd, MedChemExpress

Product Code. p-200097390
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Quantity:
1 mg
5 mg
10 mg
Unit Size:
10mg
1mg
5mg
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Product Code. 16495778

Brand: Medchem Express HY13631D

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Description

MedChemExpress Dxd (Exatecan derivative for ADC) is a potent DNA topoisomerase I inhibitor, with an IC50 of 0.31 μM, used as a conjugated drug of HER2-targeting ADC (DS-8201a).

Dxd (Exatecan derivative for ADC) is a potent DNA topoisomerase I inhibitor, with an IC50 of 0.31 μM, used as a conjugated drug of HER2-targeting ADC (DS-8201a).

Specifications

Chemical Name or Material Dxd
CAS 1599440-33-1
Color Off-White
Purity Grade Notes Research
Molecular Formula C26H24FN3O6
Quantity 10 mg
Synonym Exatecan derivative for ADC
Solubility Information DMSO : 7.14 mg/mL (14.47 mM; Need ultrasonic)
SMILES O=C1[C@](O)(CC)C2=C(CO1)C(N3CC4=C5C6=C(CC[C@@H]5NC(CO)=O)C(C)=C(F)C=C6N=C4C3=C2)=O
Molecular Weight (g/mol) 493.48
Formula Weight 493.48
Percent Purity 98.02%
Grade Research
Physical Form Powder
For Use With (Application) Cancer-programmed cell death
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Research purposes only

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