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Invitrogen™ DUOX1 Polyclonal Antibody
Rabbit Polyclonal Antibody
Brand: Invitrogen™ PA585452
This item is not returnable.
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Description
Keep as concentrated solution. Predicted reactivity: Mouse (89%), Rat (87%), Dog (86%), Pig (90%), Bovine (90%). Positive Control: A549, H1299, HCT116, unboiled A431, A431 membrane extract. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
The protein encoded by this gene is a glycoprotein and a member of the NADPH oxidase family. The synthesis of thyroid hormone is catalyzed by a protein complex located at the apical membrane of thyroid follicular cells. This complex contains an iodide transporter, thyroperoxidase, and a peroxide generating system that includes this encoded protein and DUOX2. This protein is known as dual oxidase because it has both a peroxidase homology domain and a gp91phox domain. Two alternatively spliced transcript variants encoding the same protein have been described for this gene.
Specifications
| DUOX1 | |
| Polyclonal | |
| Unconjugated | |
| DUOX1 | |
| 9930101G15Rik; AW987690; Dual oxidase 1; dual oxidase 2; DUOX; DUOX1; Duox2; flavoprotein NADPH oxidase; large NOX 1; LNOX1; LNOX2; long NOX 1; NADPH thyroid oxidase 1; nicotinamide adenine dinucleotide phosphate oxidase; NOXEF1; NOXEF2; P138-TOX; THOX1; THOX2; thyroid oxidase 1 | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 53905 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
| Immunohistochemistry (Paraffin), Western Blot | |
| 0.5 mg/mL | |
| PBS with 20% glycerol and 0.025% ProClin 300; pH 7 | |
| Q9NRD9 | |
| DUOX1 | |
| Recombinant protein encompassing a sequence within the Extracellular domain of human DUOX1. The exact sequence is proprietary. | |
| 100 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG |
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