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Tocris Bioscience™ DEL 22379

ERK dimerization inhibitor
Brand: Tocris Bioscience™ 5774/50
This item is not returnable.
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Description
DEL 22379 is an ERK dimerization inhibitor (IC50 ∽ 0.5 μM); inhibits ERK dimerization without affecting phosphorylation or kinase activity. Suppresses growth of tumor cells expressing RAS-ERK oncogenes in vitro. Induces apoptosis and prevents tumor progression in vivo.Specifications
| N-[2,3-Dihydro-3-[(5-methoxy-1H-indol-3-yl)methylene]-2-oxo-1H-indol-5-yl]-1-piperidinepropanamide | |
| 181223-80-3 | |
| 50 mg |
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