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dBET6, MedChemExpress

Product Code. 16453186
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Product Code. 16453186 Supplier Medchem Express Supplier No. HY112588

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Description

MedChemExpress dBET6 is a highly potent, selective and cell-permeable PROTAC connected by ligands for Cereblon and BET, with an IC50 of 14 nM, and has antitumor activity.

dBET6 is a highly potent, selective and cell-permeable PROTAC connected by ligands for Cereblon and BET, with an IC50 of 14 nM, and has antitumor activity.

Specifications

Chemical Name or Material dBET6
CAS 1950634-92-0
Color Off-White
Purity Grade Notes Research
Molecular Formula C42H45ClN8O7S
Quantity 25 mg
Solubility Information DMSO : 50 mg/mL (59.43 mM; Need ultrasonic)
SMILES O=C(NCCCCCCCCNC(COC1=CC=CC(C(N2C(CC3)C(NC3=O)=O)=O)=C1C2=O)=O)C[C@H]4C5=NN=C(C)N5C6=C(C(C)=C(C)S6)C(C7=CC=C(Cl)C=C7)=N4
Molecular Weight (g/mol) 841.37
Formula Weight 841.37
Percent Purity 98.12%
Grade Research
Physical Form Powder
For Use With (Application) Cancer-programmed cell death
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Research purposes only

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