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dBET57, MedChemExpress
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Quantity:
5 mg
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5mg
Description
dBET57 is a potent and selective degrader of BRD4BD1 based on the PROTAC technology. dBET57 mediates recruitment to the CRL4Cereblon E3 ubiquitin ligase, with a DC50/5h of 500 nM for BRD4BD1, and is inactive on BRD4BD2.
Specifications
Specifications
| Chemical Name or Material | dBET57 |
| CAS | 1883863-52-2 |
| Color | Yellow |
| Purity Grade Notes | Research |
| Molecular Formula | C34H31ClN8O5S |
| Quantity | 50 mg |
| Solubility Information | DMSO : 250 mg/mL (357.56 mM; Need ultrasonic) |
| SMILES | O=C(NCCNC1=CC=CC(C(N2C(CC3)C(NC3=O)=O)=O)=C1C2=O)C[C@H]4C5=NN=C(C)N5C6=C(C(C)=C(C)S6)C(C7=CC=C(Cl)C=C7)=N4 |
| Molecular Weight (g/mol) | 699.18 |
| Formula Weight | 699.18 |
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Research purposes only
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