missing translation for 'onlineSavingsMsg'
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Description
GRP1 (general receptor for phosphoinositides-1) contains a Pleckstrin homology (PH) domain as well as a Sec7 domain. The PH domain has high binding affinity for phosphatidylinositol 3,4,5-trisphosphate Ptdlns(3,4,5)P3), while the Sec7 homology domain is responsible for catalyzing guanine nucleotide exchange of ADP-ribosylation factor (ARF) proteins. GRP1 co-localizes with ARF6 and catalyzes GTP/GDP exchange on ARF6. It is known to interact with Ptdlns(3,4,5)P3 localized to the plasma membrane in vitro and may also be a Ptdlns(3,4,5)P3 receptor. Additionally, GRP1 may regulate protein sorting and membrane trafficking through interaction with the guanosine triphosphate ARF, and may control cell adhesion through interaction with integrins.
Specifications
Specifications
| Antigen | Cytohesin 3 |
| Applications | Western Blot |
| Classification | Polyclonal |
| Concentration | 0.48 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 |
| Gene | CYTH3 |
| Gene Accession No. | O08967, O43739, P97696 |
| Gene Alias | ARNO3, CYTH3, cytohesin 3, GRP1, Protein ARNO3, PSCD3 |
| Gene Symbols | Cyth3 |
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Product Title
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