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Invitrogen™ Cyclin F Polyclonal Antibody

Description
Immunogen sequence: YRQVSLTAVKQ RFEDKRYGEI SQEEVLSYSQ LCAALGVTQD SPDPPTFLST GEIHAFLSSP SGRRTKRKRE N Highest antigen sequence identity to the following orthologs - mouse 78%, rat 82%.
This gene encodes a member of the cyclin family. Cyclins are important regulators of cell cycle transitions through their ability to bind and activate cyclin-dependent protein kinases. This member also belongs to the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and it was one of the first proteins in which the F-box motif was identified.
Specifications
Specifications
| Antigen | Cyclin F |
| Applications | Immunocytochemistry |
| Classification | Polyclonal |
| Concentration | 0.05 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 40% glycerol and 0.02% sodium azide; pH 7.2 |
| Gene | CCNF |
| Gene Accession No. | P41002 |
| Gene Alias | CCNF; CDK2; CycF; cyclin F; cyclin-F; EC 2.7.11.22; F-box only protein 1; FBX1; Fbxo1; G2/mitotic-specific cyclin-F; P33(CDK2) |
| Gene Symbols | CCNF |
| Show More |
Product Title
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