missing translation for 'onlineSavingsMsg'
Learn More
Learn More
CRKRS Rabbit anti-Human, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Brand: Proteintech 26816-1-AP-20UL
This item is not returnable.
View return policy
Description
Plays important functions in early cell signaling. Binds the cAMP response element (CRE) (consensus: 5′-GTGACGT[AG][AG]-3′), a sequence present in many viral and cellular promoters. Activator of the NF-ELAM1/delta-A site of the E-selectin promoter. Has no intrinsic transcriptional activity, but activates transcription on formation of JUN or FOS heterodimers. Also can bind TRE promoter sequences when heterodimerized with members of the JUN family. Isoform 4/ATF-A0acts as a domit repressor of the E-selectin/NF-ELAM1/delta-A promoter. Isoform 5/ATF-4acts as a negative regulator, inhibiting both ATF2 and ATF7 transcriptional activities. It may exert these effects by sequestrating in the cytoplasm the Thr-53 phosphorylating kinase, preventing activation.Specifications
| CRKRS | |
| Polyclonal | |
| Unconjugated | |
| CDK12 | |
| CDC2 related protein kinase 7, CDK12, CRK7, CRKR, CRKRS, KIAA0904 | |
| Rabbit | |
| Antigen Affinity Chromatography | |
| RUO | |
| 51755 | |
| -20°C | |
| Liquid |
| Immunoprecipitation, Immunofluorescence, Immunocytochemistry, Western Blot | |
| 0.4 mg/mL | |
| PBS with 50% glycerol and 0.1% sodium azide; pH 7.3 | |
| Q9NYV4 | |
| CDK12 | |
| CRKRS Fusion Protein Ag25323 | |
| 20 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG |
Product Content Correction
Your input is important to us. Please complete this form to provide feedback related to the content on this product.
Product Title
Spot an opportunity for improvement?Share a Content Correction