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Invitrogen™ COL9A1 Polyclonal Antibody
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Product Code. 16598361
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Quantity:
100 μL
Unit Size:
100µL
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16598361 100 μL 100µL
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Product Code. 16598361 Supplier Invitrogen™ Supplier No. PA593062

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Description

Rabbit Polyclonal Antibody

Immunogen sequence: WASAAVKRRP RFPVNSNSNG GNELCPKIRI GQDDLPGFDL ISQFQVDKAA SRRAIQRVVG SATLQVAYKL GNNVDFRIPT RNLYPSGLPE EYSFLTTFRM TGSTLKKNWN IWQIQDSSGK EQVGIKINGQ TQSVVFSYKG LDGSLQTAAF SNLSSLFDSQ WHKIMIGVER SSATLFVDCN RIESLPIKPR GPIDIDGFAV LGKLADNPQV SVPFELQWML IHCDPLRPRR ETCHELPARI TPSQTTDERG P; Positive Samples: Mouse skeletal muscle; Cellular Location: extracellular matrix, extracellular space.

COL9A1 is one of the three alpha chains of type IX collagen, which is a minor (5-20%) collagen component of hyaline cartilage. Type IX collagen is usually found in tissues containing type II collagen, a fibrillar collagen. Studies in knockout mice have shown that synthesis of the alpha 1 chain is essential for assembly of type IX collagen molecules, a heterotrimeric molecule, and that lack of type IX collagen is associated with early onset osteoarthritis. Mutations in the COL9A1 gene are associated with osteoarthritis in humans, with multiple epiphyseal dysplasia, 6, a form of chondrodysplasia, and with Stickler syndrome, a disease characterized by ophthalmic, orofacial, articular, and auditory defects.
TRUSTED_SUSTAINABILITY

Specifications

Antigen COL9A1
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 1.09 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene COL9A1
Gene Accession No. P20850
Gene Alias alpha 1 type IX collagen; alpha-1(IX) collagen chain; cartilage-specific short collagen; COL9A1; Col9a-1; Collagen alpha-1(IX) chain; collagen IX, alpha-1 polypeptide; collagen type IX alpha 1; collagen, type IX, alpha 1; DJ149L1.1.2; EDM6; MED; procollagen, type IX, alpha 1; STL4
Gene Symbols COL9A1
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 20-270 of human COL9A1 (NP_0018423).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 305104
Target Species Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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