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Description
Chlorhexidine is a cationic broad-spectrum antimicrobial agent belonging to the bis(biguanide) family. Its mechanism of action involves destabilization of the outer bacterial membrane. It is used primarily as a topical antiseptic/disinfectant in wound healing, at catheterization sites, in various dental applications and in surgical scrubs.
- It is an agent to prevent gingivitis and was used to study the effects of antimicrobials on dental plaque
- Commercial ophthalmic products have used this agent to replace thimerosal as a preservative; however, it can cause skin irritation
- It has been used to study the inactivation of HIV and the immobilization of sperm
- It was used to study effective skin antisepsis and disinfection of medical devices
Specifications
Specifications
| CAS | 56-95-1 |
| Melting Point | 151°C to 159°C |
| Molecular Formula | C26H38Cl2N10O4 |
| MDL Number | MFCD00150042 |
| Quantity | 100 g |
| Synonym | chlorhexidine acetate hydrate 1:2:x, chlorhexidine diacetate salt monohydrate, chlorhexidine diacetate monohydrate, 1,1 inverted exclamation marka-hexamethylenebis 5-4-chlorophenyl biguanide diacetate salt, 4-chlorophenyl 6-4-chlorophenyl amino iminomethyl amino iminomethy l amino hexyl amino iminomethyl amino iminomethyl amine, acetic acid, acetic a cid, oxamethane |
| Solubility Information | Soluble in water (0.15g/10mL water with heat), in ethanol (50mg/mL - clear, faint yellow solution), alcohol, glycerol, propylene, glycol, polyethylene glycols. |
| InChI Key | WDRFFJWBUDTUCA-UHFFFAOYSA-N |
| SMILES | CC(O)=O.CC(O)=O.NC(NC1=CC=C(Cl)C=C1)=NC(N)=NCCCCCCN=C(N)N=C(N)NC1=CC=C(Cl)C=C1 |
| IUPAC Name | acetic acid;(1E)-2-[6-[[amino-[(E)-[amino-(4-chloroanilino)methylidene]amino]methylidene]amino]hexyl]-1-[amino-(4-chloroanilino)methylidene]guanidine;hydrate |
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