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Invitrogen™ CHKB Polyclonal Antibody

Product Code. 15761781 Shop All Thermo Scientific Products
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Quantity:
100 μL
Unit Size:
100µL
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15761781 100 μL 100µL
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Product Code. 15761781 Supplier Invitrogen™ Supplier No. PA553847

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Description

Rabbit Polyclonal Antibody

Immunogen sequence: CEWVYDYTHE EWPFYKARPT DYPTQEQQLH FIRHYLAEAK KGETLSQEEQ RKLEEDLLVE VSRYALASHF FWGLWS Highest antigen sequence identity to the following orthologs: Mouse - 84%, Rat - 84%.

The major pathway for the biosynthesis of phosphatidylcholine occurs via the CDP-choline pathway. Choline kinase, the initial enzyme in the sequence, plays a role in cell growth proliferation. A related protein, ChoKB (also, known as choline kinase beta), is a 395 amino acid enzyme that catalyzes the phosphorylation of choline by ATP in the presence of magnesium, thereby yielding phosphocholine and ADP. Like all choline kinases, ChoKB possesses ethanoalamine kinase activity and catalyzes the phosphorylation of ethanolamine. The gene encoding ChoKB is located less than 1 kb upstream of the CPT1B gene, suggesting that the ChoKB gene may regulate transcription CPT1B. In mice, mutations and/or deletions in the gene encoding ChoKB are the cause of hindlimb muscular dystrophy and neonatal bone deformity.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CHKB
Applications Immunohistochemistry (Paraffin), Immunocytochemistry
Classification Polyclonal
Concentration 0.05 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene CHKB
Gene Accession No. Q9Y259
Gene Alias Chetk; CHKB; Chkl; choline kinase beta; Choline kinase-like protein; choline/ethanolamine kinase; choline/ethanolamine kinase beta; choline/ethanolamine kinase-b; choline/ethanolaminekinase; CK; Ck/Ek; Ck/Ek-beta; CKB; CKEKB; EK; EKB; ethanolamine kinase; Ethanolamine kinase beta; MDCMC
Gene Symbols CHKB
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human CHKB. Recombinant protein control fragment (Product #RP-92367).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1120
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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