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Cenerimod, MedChemExpress

Product Code. 16447396
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Product Code. 16447396 Supplier Medchem Express Supplier No. HY17606

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Description

MedChemExpress Cenerimod (ACT-334441) is a potent, selective and orally active S1P1 receptor modulator, with an EC50 of 1 nM. Cenerimod shows more than 36‐fold selctivity for hS1P1 over hS1P2, hS1P3, hS1P4, and hS1P5 receptor subtypes (EC50s=>10000, 228, 2134, and 36 nM, respectively). Cenerimod can attenuate murine experimental autoimmune encephalomyelitis (EAE) and murine sclerodermatous.

Cenerimod (ACT-334441) is a potent, selective and orally active S1P1 receptor modulator, with an EC50 of 1 nM. Cenerimod shows more than 36‐fold selctivity for hS1P1 over hS1P2, hS1P3, hS1P4, and hS1P5 receptor subtypes (EC50s=>10000, 228, 2134, and 36 nM, respectively). Cenerimod can attenuate murine experimental autoimmune encephalomyelitis (EAE) and murine sclerodermatous.

Specifications

Chemical Name or Material Cenerimod
CAS 1262414-04-9
Color White
Purity Grade Notes Research
Molecular Formula C25H31N3O5
Quantity 100 mg
Synonym ACT-334441
Solubility Information DMSO : ≥ 100 mg/mL (220.49 mM)
SMILES OC[C@H](O)COC1=C(C)C=C(C2=NOC(C3=CC(C4CCCC4)=NC(OC)=C3)=N2)C=C1CC
Molecular Weight (g/mol) 453.53
Formula Weight 453.53
Percent Purity 98.0%
Grade Research
Physical Form Solid
For Use With (Application) COVID-19-immunoregulation
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Research purposes only

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