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Invitrogen™ Human CDK18/cyclin Y, GST Tag Recombinant Protein

Product Code. 17108775
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10 μg
100 μg
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10µg
1mg
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17108775 1 mg 1mg
15980273 10 μg 10µg
17188725 100 μg 100µg
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Product Code. 17108775 Supplier Invitrogen™ Supplier No. A33352

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Description

Recombinant Protein

For maximum recovery please spin prior to use. Unless noted below, aliquots of the 5 μg, 10 μg and 20 μg sizes of kinase are not recommended as materials can be used in original packaging until exhausted. For larger sizes, the number of freeze/thaws may be reduced by preparing aliquots, aliquots below 20 μL are not recommended. Please never store a kinase diluted. If properly stored at -80C, this product is guaranteed for 6 months from date of purchase. This CDK18/cyclin Y recombinant human protein (CDK18: full length, cyclin Y: 2-end) was expressed in insect cells. CDK18/cyclin Y recombinant human protein is also available in our SelectScreen™ Kinase Profiling Service. Validated for use with the Z'-LYTE™ assay Available in multiple pack sizes for convenient use Also available in our SelectScreen Kinase Profiling Service Protein Form: Recombinant, Active, Catalytic The gene accession number for CDK18/cyclin Y are AAH11526 and NP_659449.3.

CDK18/cyclin Y serine/threonine kinase or cyclin-dependent kinase 18 belongs to the cdc2/cdkx subfamily of kinases. CDK18/cyclin Y is thought to play a role in terminally differentiated neurons and it contains an N-terminal extension relative to CDC2. CDK18/cyclin Y is expressed in a variety of human cell lines and tissues. Elevation in the protein levels of CDK18/cyclin Y in the temporal cortex of Alzheimer's disease relative to control brains has been observed. It is proposed that CDK18/cyclin Y is a paired helical filaments-associated kinase that modulates tau phosphorylation.
TRUSTED_SUSTAINABILITY

Specifications

Accession Number Q07002
Concentration See Label
For Use With (Application) Kinase Assay
Formulation 50mM tris HCl with 25% glycerol, 10mM glutathione, 0.1mM EDTA, 0.1mM PMSF, 150mM NaCl, 0.25mM DTT and no preservative; pH 7.5
Gene ID (Entrez) 5129
Molecular Weight (g/mol) 80.5-65.5 kDa
Name Human CDK18/cyclin Y, GST Tag
pH Range 7.5
Purification Method Purified
Quantity 1 mg
Storage Requirements -80°C, Avoid Freeze/Thaw Cycles
Regulatory Status RUO
Gene Alias PCTK3
Common Name CDK18
Gene Symbol CDK18
KinaseFamily CDKs and CHKs
Product Type Protein
Conjugate Unconjugated
Species Human
Recombinant Recombinant
Protein Tag GST-tag
Sequence CDK18: Full Length, Cyclin Y: 2-341
Content And Storage -80°C, Avoid Freeze/Thaw Cycles
Shipping Condition Dry Ice
Expression System Insect cells
Protein Form Recombinant, Active, Catalytic
Form Liquid
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