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  4. Invitrogen™ Human CDC42 BPA (MRCKA), His Tag Recombinant Protein

Invitrogen™ Human CDC42 BPA (MRCKA), His Tag Recombinant Protein

Product Code. 10425022
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Quantity:
1 mg
10 μg
Unit Size:
10µg
1mg
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Product Code. 10425022

Brand: Invitrogen™ PV4434

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This item is not returnable. View return policy

Description

Recombinant Protein

For maximum recovery please spin prior to use. Unless noted below, aliquots of the 5 μg, 10 μg and 20 μg sizes of kinase are not recommended as materials can be used in original packaging until exhausted. For larger sizes, the number of freeze/thaws may be reduced by preparing aliquots, aliquots below 20 μL are not recommended. Please never store a kinase diluted. If properly stored at -80C, this product is guaranteed for 6 months from date of purchase. Protein Form: Catalytic.

CDC42BPA (MRCKA) is a serine/threonine kinase which functions in actin cytoskeleton assembly and organization. Three independent coiled-coil domains and the N-terminal region preceding the kinase domain are responsible for intermolecular interactions leading to MRCK alpha multimerization. The transautophosphorylation process is critical for regulation of MRCK alpha catalytic activities. Binding of phorbol esters to MRCK releases its autoinhibition, allowing N-terminal dimerization and subsequent kinase activation.
TRUSTED_SUSTAINABILITY

Specifications

Accession Number Q5VT25
Concentration See Label
For Use With (Application) Kinase Assay
Formulation 50mM tris with 50% glycerol, 0.02% Triton X-100, 2mM DTT, 150mM NaCl, 0.5mM EDTA and no preservative; pH 7.5
Gene ID (Entrez) 8476
Molecular Weight (g/mol) 58.7 kDa
Name Human CDC42 BPA (MRCKA), His Tag
pH Range 7.5
Purification Method Purified
Quantity 1 mg
Storage Requirements -80°C, Avoid Freeze/Thaw Cycles
Regulatory Status RUO
Gene Alias A930014J19Rik; CDC42 binding protein kinase alpha; CDC42 binding protein kinase alpha (DMPK-like); CDC42 binidng protein kinase beta; CDC42-binding protein kinase alpha; CDC42-binding protein kinase alpha (DMPK-like); CDC42BPA; cdc42bpa {ECO:0000250; DKFZp686L1738; DKFZp686P1738; DMPK-like; DMPK-like alpha; FLJ23347; Kiaa0451; MRCK; MRCK alpha; MRCKA; myotonic dystrophy kinase-related CDC42-binding kinase alpha; myotonic dystrophy kinase-related CDC-42-binding kinase-alpha; myotonic dystrophy kinase-related CDC42-binding protein kinase alpha; myotonic dystrophy protein kinase-like alpha; mytonic dystrophy kinase-related Cdc42-binding kinase; PK428; RP5-1087E8.4; serine/threonine-protein kinase MRCK alpha; ser-thr protein kinase PK428; ser-thr protein kinase related to the myotonic dystrophy protein kinase; UniProtKB:Q5VT25}
Common Name MRCK alpha
Gene Symbol CDC42BPA
KinaseFamily DMPK Kinase Family
Protein Length 1-473
Product Type Protein
Conjugate Unconjugated
Species Human
Recombinant Recombinant
Protein Tag His-tag
Sequence 1-473
Content And Storage -80°C, Avoid Freeze/Thaw Cycles
Kinase Group Ser/Thr Kinases: AGC Group
Shipping Condition Dry Ice
Expression System Baculovirus
Protein Family Kinases & Inhibitors
Protein Form Catalytic
Form Liquid
Research Category Drug Development
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