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  6. CD62L (L-selectin) Rat, anti-Mouse, PE, Clone: MEL-14, STEMCELL Technologies

CD62L (L-selectin) Rat, anti-Mouse, PE, Clone: MEL-14, STEMCELL Technologies

Rat Monoclonal Antibody

POA - 321.30 EUR

Specifications

Antigen CD62L (L-selectin)
Clone MEL-14
Applications CyTOF, Flow Cytometry, Immunocytochemistry, Immunofluorescence, Functional Assay
Classification Monoclonal
Conjugate PE
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17169081
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Stemcell Technologies
60109PE.1 		25 μg This item is currently unavailable or has been discontinued.
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Stemcell Technologies
60109PE 		100 μg
321.30 EUR
100µg
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Description

Description

  • The MEL-14 antibody reacts with murine CD62L (L-Selectin or LECAM-1), an ∼74 - 95 kDa type I glycoprotein expressed on the surface of a majority of leukocytes
  • CD62L mediates leukocyte-endothelial cell interactions through its association with ligands such as CD34, glyCAM-1, MAdCAM-1 and PSGL-1
  • It functions to facilitate lymphocyte rolling on the vascular endothelium, trafficking of lymphocytes to the lymph nodes, and homing of lymphocytes and neutrophils to sites of inflammation
  • Murine CD62L is expressed on most thymocytes, the highest expression levels being found on subsets of immunocompetent or dividing progenitor cells, as well as on neutrophils, eosinophils, monocytes, and subsets of B, T and NK cells
  • The MEL-14 antibody may be used together with antibodies to other cell surface markers to distinguish naive, memory and effector T cells
  • The MEL-14 antibody has been shown to block migration of lymphocytes to lymph nodes and to inhibit leukocyte rolling
Specifications

Specifications

CD62L (L-selectin)
CyTOF, Flow Cytometry, Immunocytochemistry, Immunofluorescence, Functional Assay
PE
Mouse
Primary
MEL-14
Monoclonal
Rat
IgG2a κ
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