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  6. CD103 (Integrin alpha E) Monoclonal Antibody (2E7), Biotin, eBioscience™, Invitrogen™

CD103 (Integrin alpha E) Monoclonal Antibody (2E7), Biotin, eBioscience™, Invitrogen™

Product Code. 15239669
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Product Code. 15239669 Supplier Invitrogen Supplier No. 13103181

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Description

Armenian Hamster Monoclonal Antibody

Description: The 2E7 monoclonal antibody reacts with mouse CD103, the alphaE integrin. CD103 non-covalently associates with integrin beta7 and is expressed on all intraepithelial lymphocytes, a small subset of peripheral lymphocytes, and dendritic epidermal T cells (DEC). Epithelial cell antigen E-cadherin binds to CD103 and mediates homing of lymphocytes to the intestinal epithelium. Applications Reported: This 2E7 antibody has been reported for use in flow cytometric analysis, and immunohistochemical staining of frozen tissue sections. Applications Tested: The 2E7 antibody has been tested by flow cytometric analysis of mouse splenocytes. This can be used at less than or equal to 0.25 μg per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest. Filtration: 0.2 μm post-manufacturing filtered.

The CD103 antigen is a 160-130-105 kDa molecule which is expressed on mucosa-associated T lymphocytes and activated cells and on subet of TGF beta -1 cells. This human intra epithelial lymphocyte marker is the E integrin chain associated with the b7 subunit. CD103 antibody stains a few bone marrow cells and, rarely, peripheral blood lymphocytes. CD103 is expressed by 0.5 to 2% of resting lymphocytes in peripheral blood and lymphoid organs.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CD103 (Integrin alpha E)
Applications Flow Cytometry, Immunohistochemistry (Frozen)
Classification Monoclonal
Clone 2E7
Concentration 0.5 mg/mL
Conjugate Biotin
Formulation PBS with 0.1% gelatin and 0.09% sodium azide; pH 7.2
Gene Itgae
Gene Accession No. Q60677
Gene Alias ITGAE, HUMINAE
Gene Symbols Itgae
Host Species Armenian Hamster
Purification Method Affinity chromatography
Quantity 50 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 16407
Target Species Mouse
Content And Storage 4° C, store in dark, DO NOT FREEZE!
Product Type Antibody
Form Liquid
Isotype IgG
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For Research Use Only.

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