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Invitrogen™ CBX4 Recombinant Rabbit Monoclonal Antibody (1R5G6)
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Product Code. 17146303
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Quantity:
100 μL
Unit Size:
100µL
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17146303 100 μL 100µL
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Product Code. 17146303 Supplier Invitrogen™ Supplier No. MA535645

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Description

Rabbit Recombinant Monoclonal Antibody

CBX4 Recombinant Monoclonal Antibody for Western Blot, IP, ELISA

Polycomb group (PcG) proteins are chromatin-associated proteins which are important for embryonic and adult stem cell self-renewal and maintenance. At least two distinct human PcG complexes have been identified. Polycomb repressive complex I (PRC1) contains CBX4/Pc2, HPH1 and RING domain-containing proteins (RING1, RING2 and BMI1). CBX4 (Chromobox protein homolog 4 or PC2), which functions as a transcriptional suppressor, is a candidate of KyoT2-binding proteins. It is a E3 SUMO-protein ligase which facilitates SUMO1 conjugation. Depletion of CBX4 results in decreased cellular resistance to ionizing radiation. CBX4 is directly involved in the cellular response to DNA damage.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CBX4
Applications ELISA, Immunoprecipitation, Western Blot
Classification Recombinant Monoclonal
Clone 1R5G6
Concentration 0.35 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene CBX4
Gene Accession No. O00257, O55187
Gene Alias Cbx4; chromobox 4; chromobox homolog 4; chromobox homolog 4 (Pc class homolog, Drosophila); chromobox protein homolog 4; chromobox-like protein 4; E3 SUMO-protein ligase CBX4; E3 SUMO-protein transferase CBX4; hPc2; MPc2; NBP16; NS5ATP1-binding protein 16; Pc class 2 homolog; PC2; Polycomb 2 homolog
Gene Symbols CBX4
Host Species Rabbit
Immunogen A synthetic peptide corresponding to amino acids 461-560 of human CBX4.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 12418, 501403, 8535
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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