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Invitrogen™ Caspase 1 Polyclonal Antibody
Rabbit Polyclonal Antibody
Brand: Invitrogen™ PA5119002
This item is not returnable.
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Description
Caspase 1 Polyclonal Antibody for Western Blot, ICC/IF, IHC (P)
Caspases are a family of cysteine proteases that can be divided into the apoptotic and inflammatory caspase subfamilies. Unlike the apoptotic caspases, members of the inflammatory subfamily are generally not involved in cell death but are associated with the immune response to microbial pathogens. Members of this subfamily include caspase-1, -4, -5, and -12 and can activate proinflammatory cytokines such as IL-1-b and IL-18. Caspase-1 was initially identified as an IL-1-b-converting enzyme; later experiments revealed it to be a mammalian homolog of the C. elegans cell death gene ced-3 whose overexpression can induce apoptosis in fibroblasts.
Specifications
| Caspase 1 | |
| Polyclonal | |
| Unconjugated | |
| CASP1 | |
| CASP1; CASP-1; CASP1 nirs variant 1; caspase 1; caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase); Caspase1; caspase-1; Caspase-1 subunit p10; Caspase-1 subunit p20; ICE; IL-1 beta-converting enzyme; IL-1B converting enzyme; IL1BC; IL-1BC; IL1BCE; IL1B-convertase; interleukin 1 beta-converting enzyme; interleukin 1, beta, convertase; interleukin 1-B converting enzyme; Interleukin 1beta converting enzyme; interleukin-1 beta convertase; Interleukin-1 beta-converting enzyme; p45 | |
| Rabbit | |
| Antigen affinity chromatography, Protein A | |
| RUO | |
| 12362, 397319, 834 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
| Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry | |
| 0.5 mg/mL | |
| PBS with 50% glycerol and 0.05% ProClin 300; pH 7.4 | |
| P29452, P29466, Q9N2I1 | |
| CASP1 | |
| Recombinant protein Caspase 1. The antigen corresponds to amino acid range 317-404 of the target protein. | |
| 200 μL | |
| Primary | |
| Human, Mouse, Pig | |
| Antibody | |
| IgG |
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