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Invitrogen™ Calreticulin Polyclonal Antibody
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Product Code. 11518861
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Quantity:
100 μL
Unit Size:
100µL
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11518861 100 μL 100µL
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Product Code. 11518861 Supplier Invitrogen™ Supplier No. PA3900

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Description

Rabbit Polyclonal Antibody

PA3-900 detects calreticulin from human, non-human primate, rabbit, mouse, canine and rat samples. PA3-900 has been successfully used in Western blot, immunofluorescence, immunocytochemistry, flow cytometry, and immunoprecipitation procedures. By Western blot, this antibody detects an ~60 kDa protein representing calreticulin from rat brain extract. Immunofluorescence staining of calreticulin in rat brain cortex with PA3-900 results in fine granular staining consistent with ER localization. PA3-900 immunogen is recombinant human calreticulin protein produced in the Baculovirus insect cell system.

Calr or Calreticulin is a calcium-binding chaperone that promotes folding, oligomeric assembly and quality control in the endoplasmic reticulum (ER) via the calreticulin/calnexin cycle. Calr, a lectin, interacts transiently with almost all of the monoglucosylated glycoproteins that are synthesized in the ER. Calr also interacts with with the DNA-binding domain of NR3C1 and mediates its nuclear export. It may also be involved in maternal gene expression regulation and oocyte maturation via the regulation of calcium homeostasis.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Calreticulin
Applications Flow Cytometry, Immunohistochemistry, Immunoprecipitation, Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration Conc. Not Determined
Conjugate Unconjugated
Formulation Whole serum with 0.05% sodium azide
Gene CALR
Gene Accession No. P14211, P15253, P18418, P27797, P28490
Gene Alias Autoantigen RO; CABP3; CALBP; calcium-binding protein 3; CALR; calrectulin; calregulin; Calreticulin; calreticulin precursor; cC1qR; CRP55; CRT; CRTC; Endoplasmic reticulum resident protein 60; epididymis secretory sperm binding protein Li 99n; ERp60; FLJ26680; grp60; HACBP; HEL-S-99n; I79_008346; RO; Ro/SS-A Antigen; Sicca syndrome antigen A (autoantigen Ro; calreticulin); SSA
Gene Symbols CALR
Host Species Rabbit
Immunogen Recombinant, human calreticulin protein.
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 100009050, 100350417, 12317, 476694, 64202, 811
Target Species Human, Mouse, Rat, Canine, Rabbit, Monkey
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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