missing translation for 'onlineSavingsMsg'
Learn More
  1. Home
  2. Products
  3. Recombinant Proteins
  4. Eurofins DiscoverX BTK Protein, Active

Eurofins DiscoverX BTK Protein, Active

Product Code. 17340334
Encompass_Preferred
Change view
Click to view available options
Quantity:
10 μg
250 μg
Unit Size:
10µg
250µg
2 product options available for selection
Product selection table with 2 available options. Use arrow keys to navigate and Enter or Space to select.
Product Code. Quantity unitSize
17340334 10 μg 10µg
17350334 250 μg 250µg
Use arrow keys to navigate between rows. Press Enter or Space to select a product option. 2 options available.
2 options
This item is not returnable. View return policy
Product Code. 17340334 Supplier Eurofins DiscoverX Supplier No. 14552

Please to purchase this item. Need a web account? Register with us today!

This item is not returnable. View return policy

Description

Active, N-terminal His6-tagged, recombinant, full-length, human BTK, for use in Kinase Assays.

BTK (Bruton's Tyrosine Kinase) is a member of the Tec family kinases which are important components of both antigen receptor signaling and other cell surface receptors, resulting in regulation of the actin cytoskeleton, adhesion, migration, and transcriptional activation. BTK is found in all cells of the hematopoietic lineage except plasma and T cells, and is required for normal B cell development and signal transduction through cell surface molecules. Mutations in the btk gene result in aberrant B cell development, leading to the X-linked agammaglobulinemia phenotype in humans and to the less severe X-linked immunodeficiency in mice. BTK inhibitors may be of benefit in the treatment of leukemias and lymphomas.

GenBank NM_000061

Specifications

Formulation mg/mL of enzyme in 50 mM Tris/HCl pH 7.5, 300 mM NaCl, 0.1 mM EGTA, 0.03% Brij-35, 270 mM sucrose, 1 mM benzamidine, 0.2 mM PMSF, 0.1% 2-mercaptoethanol. Frozen solution.
Molecular Weight (g/mol) 78.4 kDa
Quantity 10 μg
Species Human
Recombinant Recombinant
Protein Tag N-terminal 6His
Expression System Recombinant enzyme expressed in Sf21 insect cells
Protein Form Full-length
Purity or Quality Grade ≥53%
Protein BTK, active
Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.