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Invitrogen™ BRK Polyclonal Antibody

Product Code. 16539541
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Quantity:
100 μL
Unit Size:
100µL
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16539541 100 μL 100µL
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Product Code. 16539541 Supplier Invitrogen™ Supplier No. PA596704

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Description

Rabbit Polyclonal Antibody

Immunogen sequence: SRDNLLHQQM LQSEIQAMKK LRHKHILALY AVVSVGDPVY IITELMAKGS LLELLRDSDE KVLPVSELLD IAWQVAEGMC YLESQNYIHR DLAARNILVG ENTLCKVGDF GLARLIKEDV YLSHDHNIPY KWTAPEALSR GHYSTKSDVW SFGILLHEMF SRGQVPYPGM SNHEAFLRVD AGYRMPCPLE CPPSVHKLML TCWCRDPEQR PCFKALRERL SSFTSYENPT; Positive Samples: SW480, BT-474, MCF7, A-549, NIH/3T3, Mouse liver, Mouse kidney, Mouse testis, Rat kidney; Cellular Location: Cell projection, Cytoplasm, Membrane, Nucleus, ruffle.

Breast tumor kinase (Brk) is a non-receptor protein tyrosine kinase expressed in over 60% of breast carcinoma tissue samples and breast tumor cell lines. Brk is 80% identity to Sik (Src-related intestinal kinase) and exhibits the features of a novel non-receptor tyrosine kinase, including amino terminal SH3 and SH2 domains. Low levels of Brk transcripts have been identified in some human breast tumor cell lines but not in normal breast tissue.
TRUSTED_SUSTAINABILITY

Specifications

Antigen BRK
Applications ELISA, Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.44 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene PTK6
Gene Accession No. Q13882, Q64434
Gene Alias ALT-PTK6; breast tumor kinase; BRK; deltam5; FLJ42088; protein tyrosine kinase 6; protein-tyrosine kinase 6; protein-tyrosine kinase BRK; Ptk6; PTK6 protein tyrosine kinase 6; Sik; SRC-related intestinal kinase; tks; Tksk; tyrosine kinase identified from skin; tyrosine-protein kinase BRK
Gene Symbols PTK6
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 222-451 of human PTK6 (NP_0059661).
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 20459, 366275, 5753
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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