missing translation for 'onlineSavingsMsg'
Learn More
  1. Home
  2. Products
  3. Chemicals
  4. Organic compounds
  5. Organoheterocyclic compounds
  6. Azoles
  7. Imidazoles
  8. BRD4770, MedChemExpress

BRD4770, MedChemExpress

Product Code. 16457146
Encompass_Preferred
Change view
Click to view available options
Quantity:
10 mg
50 mg
100 mg
Unit Size:
100mg
10mg
50mg
3 product options available for selection
Product selection table with 3 available options. Use arrow keys to navigate and Enter or Space to select.
Product Code. Quantity unitSize
16457146 100 mg 100mg
16447148 10 mg 10mg
16413177 50 mg 50mg
Use arrow keys to navigate between rows. Press Enter or Space to select a product option. 3 options available.
3 options
This item is not returnable. View return policy
Product Code. 16457146 Supplier Medchem Express Supplier No. HY16705

Please to purchase this item. Need a web account? Register with us today!

This item is not returnable. View return policy

Description

MedChemExpress BRD4770 is a histone methyltransferase G9a inhibitor. BRD4770 reduces di- and trimethylation of lysine 9 on histone H3 (H3K9) with an EC50 of 5 μM, and has less or little effect toward H3K27me3, H3K36me3, H3K4me3, and H3K79me3. BRD4770 can activate the ataxia telangiectasia mutated (ATM) pathway and induce cell senescence.

BRD4770 is a histone methyltransferase G9a inhibitor. BRD4770 reduces di- and trimethylation of lysine 9 on histone H3 (H3K9) with an EC50 of 5 μM, and has less or little effect toward H3K27me3, H3K36me3, H3K4me3, and H3K79me3. BRD4770 can activate the ataxia telangiectasia mutated (ATM) pathway and induce cell senescence.

Specifications

Chemical Name or Material BRD4770
CAS 1374601-40-7
Color White
Purity Grade Notes Research
Molecular Formula C25H23N3O3
Quantity 100 mg
Solubility Information DMSO : 33.33 mg/mL (80.61 mM; Need ultrasonic)
SMILES O=C(C1=CC=C2C(N=C(NC(C3=CC=CC=C3)=O)N2CCCC4=CC=CC=C4)=C1)OC
Molecular Weight (g/mol) 413.47
Formula Weight 413.47
Percent Purity 98.59%
Grade Research
Physical Form Powder
For Use With (Application) Cancer-programmed cell death
Show More Show Less

Research purposes only

Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.