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BRD4770, MedChemExpress

Product Code. 16413177
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Product Code. 16413177

Brand: Medchem Express HY16705

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Description

MedChemExpress BRD4770 is a histone methyltransferase G9a inhibitor. BRD4770 reduces di- and trimethylation of lysine 9 on histone H3 (H3K9) with an EC50 of 5 μM, and has less or little effect toward H3K27me3, H3K36me3, H3K4me3, and H3K79me3. BRD4770 can activate the ataxia telangiectasia mutated (ATM) pathway and induce cell senescence.

BRD4770 is a histone methyltransferase G9a inhibitor. BRD4770 reduces di- and trimethylation of lysine 9 on histone H3 (H3K9) with an EC50 of 5 μM, and has less or little effect toward H3K27me3, H3K36me3, H3K4me3, and H3K79me3. BRD4770 can activate the ataxia telangiectasia mutated (ATM) pathway and induce cell senescence.

Specifications

Chemical Name or Material BRD4770
CAS 1374601-40-7
Color White
Purity Grade Notes Research
Molecular Formula C25H23N3O3
Quantity 50 mg
Solubility Information DMSO : 33.33 mg/mL (80.61 mM; Need ultrasonic)
SMILES O=C(C1=CC=C2C(N=C(NC(C3=CC=CC=C3)=O)N2CCCC4=CC=CC=C4)=C1)OC
Molecular Weight (g/mol) 413.47
Formula Weight 413.47
Percent Purity 98.59%
Grade Research
Physical Form Powder
For Use With (Application) Cancer-programmed cell death
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Research purposes only

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