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BQ-788, MedChemExpress

Product Code. 16489437
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1 mg
5 mg
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Product Code. 16489437

Brand: Medchem Express HY15894A

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Description

MedChemExpress BQ-788 is a potent, selective ETB receptor antagonist with IC50 of 1.2 nM for inhibition of ET-1 binding to human Girardi heart cells, poorly inhibiting the binding to ETA receptors in human neuroblastoma cell line SK-N-MC cells with IC50 of 1300 nM.

BQ-788 is a potent, selective ETB receptor antagonist with IC50 of 1.2 nM for inhibition of ET-1 binding to human Girardi heart cells, poorly inhibiting the binding to ETA receptors in human neuroblastoma cell line SK-N-MC cells with IC50 of 1300 nM.

Specifications

Chemical Name or Material BQ-788
CAS 173326-37-9
Color Off-White
Purity Grade Notes Research
Molecular Formula C34H51N5O7
Quantity 5 mg
Solubility Information DMSO : 170 mg/mL (264.88 mM; ultrasonic and warming and heat to 60°C)
SMILES CCCC[C@H](C(O)=O)NC([C@@H](CC1=CN(C(OC)=O)C2=CC=CC=C12)NC([C@H](CC(C)(C)C)NC(N3[C@H](C)CCC[C@@H]3C)=O)=O)=O
Molecular Weight (g/mol) 641.8
Formula Weight 641.8
Percent Purity 98.28%
Grade Research
Physical Form Solid
For Use With (Application) Metabolism-sugar/lipid metabolism
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Research purposes only

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