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Invitrogen™ BNIP2 Polyclonal Antibody
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Product Code. 13464387
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Quantity:
100 μL
Unit Size:
100µL
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13464387 100 μL 100µL
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Product Code. 13464387 Supplier Invitrogen™ Supplier No. PA529977

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Description

Rabbit Polyclonal Antibody

Recommended positive controls: Jurkat, Raji, NCI-H929. Predicted reactivity: Mouse (91%), Rat (92%), Zebrafish (80%), Xenopus laevis (86%), Bovine (97%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

BNIP-2, (previously designated Nip2 and Nip21 in human and mouse respectively), shares homology with the non-catalytic domain of Cdc42 GTPase-activating protein (Cdc42GAP). Through binding to Cdc42GAP, BNIP-2 enhances the GTPase activity of Cdc42GAP, facilitating the hydrolysis of GTP bound to Cdc42 and thereby, mediating the signaling pathways involving receptor kinases, small GTPases and apoptotic proteins. Nix, which is also designated Nip3L or Bnip3L, is highly related to BNIP-3, and both proteins localize to the mitochondria where they associate with Bcl-2 proteins.
TRUSTED_SUSTAINABILITY

Specifications

Antigen BNIP2
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1.02 mg/mL
Conjugate Unconjugated
Formulation PBS with 20% glycerol and 0.025% ProClin 300; pH 7
Gene Bnip2
Gene Accession No. Q12982
Gene Alias 5730523P12Rik; Bcl-2 and E1B 19 kDa interacting protein; BCL2 interacting protein 2; BCL2/adenovirus E1B 19 kDa protein-interacting protein 2; BCL2/adenovirus E1B 19 kDa-interacting protein 2 beta; BCL2/adenovirus E1B 19kDa interacting protein 2; BCL2/adenovirus E1B 19kDa-interacting protein 1, NIP2; BCL2/adenovirus E1B interacting protein 1, NIP2; BCL2/adenovirus E1B interacting protein 2; BNIP 2; BNIP2; BNIP-2; BNIP2beta; NIP2; Nip21; Nip2l
Gene Symbols Bnip2
Host Species Rabbit
Immunogen Recombinant protein encompassing a sequence within the center region of human BNIP2. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 300811, 663
Target Species Human, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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