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ACROBiosystems Biotinylated Human NKG2A & CD94 Protein, Fc, Avitag™

Product Code. p-7216553
Click to view available options
Quantity:
200 μg
25 μg
Unit Size:
200µg
25µg

Product Code. 17106531

Brand: ACROBiosystems NC4H82F5200ug

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Description

Biotinylated Protein

CD94 plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells. KLRD1 (CD94) is an antigen preferentially expressed on NK cells and is classified as a type II membrane protein because it has an external C terminus. NKG2A/CD159a is a transmembrane protein belonging to the CD94/NKG2 family of C-type lectin-like receptors that inhibits innate immune system activation. CD94 pairs with the NKG2 molecule as a heterodimer. The CD94/NKG2 complex, on the surface of natural killer cells interacts with Human Leukocyte Antigen (HLA)-E on target cells.

This protein carries a human IgG1 Fc tag at the C-terminus, followed by a Avi tag (Avitag™). The protein has a calculated MW of 40.4 kDa & 42.3 kDa. The protein migrates as 50-60 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

Specifications

Accession Number NP_002250.1 (NKG2A) and N/A
Molecular Weight (g/mol) 40.4 kDa and 42.3 kDa
Quantity 200 μg
Source Biotinylated Human NKG2A&CD94;, Fc,Avitag™ (NC4-H82F5) is expressed from human 293 cells (HEK293). It contains AA Ala 113 - Leu 233 and Asp 57-Ile 179 (Accession # P26715-1 (NKG2A) and Q13241-1 (CD94)).
Immunogen Ala 113 - Leu 233 and Asp 57-Ile 179
Storage Requirements -20°C
Gene Alias NKG2A and CD94
Common Name NKG2A and CD94
Conjugate Precision Avi
Species Human
Protein Tag Fc Tag and Avi Tag
Buffer PBS, pH7.4
Endotoxin Level Less than 1.0 EU / μg by the LAL method.
Expression System HEK293
Form Powder
Protein Subtype MABSol™ Biotin Labeled Proteins
Purity or Quality Grade >95% as determined by SDS-PAGE
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