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Bimiralisib, MedChemExpress

Product Code. p-200099369
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Product Code. 16490176

Brand: Medchem Express HY12868

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Description

MedChemExpress Bimiralisib (PQR309) is a potent, brain-penetrant, orally bioavailable, pan-class I PI3K/mTOR inhibitor with IC50s of 33 nM, 451 nM, 661 nM, 708 nM and 89 nM for PI3Kα, PI3Kδ, PI3Kβ, PI3Kγ and mTOR, respectively. Bimiralisib is an mTORC1 and mTORC2 inhibitor.

Bimiralisib (PQR309) is a potent, brain-penetrant, orally bioavailable, pan-class I PI3K/mTOR inhibitor with IC50s of 33 nM, 451 nM, 661 nM, 708 nM and 89 nM for PI3Kα, PI3Kδ, PI3Kβ, PI3Kγ and mTOR, respectively. Bimiralisib is an mTORC1 and mTORC2 inhibitor.

Specifications

Chemical Name or Material Bimiralisib
CAS 1225037-39-7
Color Gray
Purity Grade Notes Research
Molecular Formula C17H20F3N7O2
Quantity 2 mg
Synonym PQR309
Solubility Information DMSO : ≥ 50 mg/mL (121.54 mM)
SMILES NC1=NC=C(C2=NC(N3CCOCC3)=NC(N4CCOCC4)=N2)C(C(F)(F)F)=C1
Molecular Weight (g/mol) 411.38
Formula Weight 411.38
Percent Purity 98.74%
Grade Research
Physical Form Solid
For Use With (Application) Cancer-Kinase/protease
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Research purposes only

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