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Benzamil hydrochloride, MedChemExpress

Product Code. 16494607
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Product Code. 16494607 Supplier Medchem Express Supplier No. HYB1546A

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Description

MedChemExpress Benzamil hydrochloride (Benzylamiloride hydrochloride), an Amiloride analogue, is a Na+/Ca2+ exchanger (NCX) inhibitor (IC50∼100 nM). Benzamil hydrochloride also is a non-selective Deg/epithelial sodium channels (ENaC) blocker, and can potentiate myogenic vasoconstriction. Benzamil hydrochloride inhibits TRPP3-mediated Ca2+-activated currents, with an IC50 of 1.1 μM.

Benzamil hydrochloride (Benzylamiloride hydrochloride), an Amiloride analogue, is a Na+/Ca2+ exchanger (NCX) inhibitor (IC50∼100 nM). Benzamil hydrochloride also is a non-selective Deg/epithelial sodium channels (ENaC) blocker, and can potentiate myogenic vasoconstriction. Benzamil hydrochloride inhibits TRPP3-mediated Ca2+-activated currents, with an IC50 of 1.1 μM.

Specifications

Chemical Name or Material Benzamil hydrochloride
CAS 161804-20-2
Color Yellow
Purity Grade Notes Research
Molecular Formula C13H15Cl2N7O
Quantity 50 mg
Synonym Benzylamiloride hydrochloride
Solubility Information DMSO : ≥ 100 mg/mL (280.73 mM) ∣H2O : < 0.1 mg/mL (insoluble)
SMILES O=C(C1=NC(Cl)=C(N)N=C1N)NC(NCC2=CC=CC=C2)=N.[H]Cl
Molecular Weight (g/mol) 356.21
Formula Weight 356.21
Percent Purity 99.6%
Grade Research
Physical Form Solid
For Use With (Application) COVID-19-immunoregulation
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Research purposes only

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