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Invitrogen™ BCLAF1 Polyclonal Antibody
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Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA585656

Product Code. 16382585

  • 520.00 EUR / 100µL

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Description

Description

Keep as concentrated solution. Predicted reactivity: Mouse (94%), Rat (94%), Pig (98%), Bovine (98%). Positive Control: 293T, A431, HeLa, HepG2. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

BCLAF1 is an intracellular, death promoting transcriptional repressor of survival genes that interacts with several members of the BCL2 family of proteins. It shows homology to the basic leucine zipper (bzip) and MYB DNA binding domains.From recent research it can be concluded that in case of apoptotic cells this protein localizes to dot-like structures throughout the nucleus, and redistributes to a zone near the nuclear envelope. When over expressed this protein induces apoptosis and can be suppressed by co-expression of BCL2 proteins. Also known as BTF, it triggers a proapoptotic signal, potentially helpful to overcome the resistance to STI571.BCLAF1 is found to express mostly in skeletal muscles.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

BCLAF1
Polyclonal
Unconjugated
BCLAF1
2610102K23Rik; 2700025J07Rik; 2810454G14Rik; 5730534O06Rik; Aa2-041; AI450190; AW556225; BCL2 associated transcription factor 1; bcl-2-associated transcription factor 1; BCL2-associated transcription factor 1; Bcl-2-associated transcription factor 1-like protein; BCLAF1; BCLAF1 and THRAP3 family member 1; bK211L9.1; BP-1; BTF; Btf-s; KIAA0164; mKIAA0164
Rabbit
Antigen affinity chromatography
RUO
9774
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Liquid
Western Blot, Immunocytochemistry, Western Blot
0.25 mg/mL
PBS with 1% BSA, 20% glycerol and 0.025% ProClin 300; pH 7
Q9NYF8
BCLAF1
Recombinant protein encompassing a sequence within the C-terminus region of human BTF. The exact sequence is proprietary.
100 μL
Primary
Human
Antibody
IgG
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