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AZ-5104, MedChemExpress

Product Code. 16498456
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Product Code. 16498456

Brand: Medchem Express HYB0793

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Description

MedChemExpress AZ-5104 is an active, demethylated metabolite of AZD 9291. AZ-5104 is an EGFR inhibitor with IC50s of 1, 6, 1, 25 and 7 nM for EGFRL858R/T790M, EGFRL858R, EGFRL861Q, EGFR and ErbB4, respectively.

AZ-5104 is an active, demethylated metabolite of AZD 9291. AZ-5104 is an EGFR inhibitor with IC50s of 1, 6, 1, 25 and 7 nM for EGFRL858R/T790M, EGFRL858R, EGFRL861Q, EGFR and ErbB4, respectively.

Specifications

Chemical Name or Material AZ-5104
CAS 1421373-98-9
Color Yellow
Purity Grade Notes Research
Molecular Formula C27H31N7O2
Quantity 100 mg
Solubility Information DMSO : ≥ 28 mg/mL (57.66 mM)
SMILES C=CC(NC1=CC(NC2=NC=CC(C3=CNC4=C3C=CC=C4)=N2)=C(OC)C=C1N(CCN(C)C)C)=O
Molecular Weight (g/mol) 485.58
Formula Weight 485.58
Percent Purity 99.34%
Grade Research
Physical Form Solid
For Use With (Application) Cancer-Kinase/protease
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Research purposes only

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