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Invitrogen™ ATF7 Polyclonal Antibody
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Product Code. 11385953
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Quantity:
100 μg
Unit Size:
100µg
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11385953 100 μg 100µg
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Product Code. 11385953 Supplier Invitrogen™ Supplier No. PA517987

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Description

Goat Polyclonal Antibody

This antibody is predicted to react with bovine, canine and rat based on sequence homology. This antibody is tested in Peptide ELISA: antibody detection limit dilution 128,000.

Plays important functions in early cell signaling. Binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AG][AG]-3'), a sequence present in many viral and cellular promoters. Activator of the NF-ELAM1/delta-A site of the E-selectin promoter. Has no intrinsic transcriptional activity, but activates transcription on formation of JUN or FOS heterodimers. Also can bind TRE promoter sequences when heterodimerized with members of the JUN family. Isoform 4/ATF-A0acts as a dominant repressor of the E-selectin/NF-ELAM1/delta-A promoter. Isoform 5/ATF-4acts as a negative regulator, inhibiting both ATF2 and ATF7 transcriptional activities. It may exert these effects by sequestrating in the cytoplasm the Thr-53 phosphorylating kinase, preventing activation.
TRUSTED_SUSTAINABILITY

Specifications

Antigen ATF7
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
Gene ATF7
Gene Accession No. P17544
Gene Alias 1110012F10Rik; 9430065F09Rik; activating transcription factor 7; AI549878; ATF7; ATFA; C130020M04Rik; cAMP-dependent transcription factor ATF-7; Cyclic AMP-dependent transcription factor ATF-7; MGC57182; transcription factor ATF-A
Gene Symbols ATF7
Host Species Goat
Immunogen Synthetic peptide sequence (HVIMTPQSQSAGR) corresponding to the C-terminus amino acids of ATF7 (aa 471-483).
Purification Method Ammonium sulfate precipitation
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 11016
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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