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ARV-771, MedChemExpress

Product Code. 16453228
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Product Code. 16453228 Supplier Medchem Express Supplier No. HY100972

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Description

MedChemExpress ARV-771 is a potent BET PROTAC based on E3 ligase von Hippel-Lindau with Kds of 34 nM, 4.7 nM, 8.3 nM, 7.6 nM, 9.6 nM, and 7.6 nM for BRD2(1), BRD2(2), BRD3(1), BRD3(2), BRD4(1), and BRD4(2), respectively.

ARV-771 is a potent BET PROTAC based on E3 ligase von Hippel-Lindau with Kds of 34 nM, 4.7 nM, 8.3 nM, 7.6 nM, 9.6 nM, and 7.6 nM for BRD2(1), BRD2(2), BRD3(1), BRD3(2), BRD4(1), and BRD4(2), respectively.

Specifications

Chemical Name or Material ARV-771
CAS 1949837-12-0
Color White
Purity Grade Notes Research
Molecular Formula C49H60ClN9O7S2
Quantity 10 mg
Solubility Information DMSO : ≥ 50 mg/mL (50.68 mM)
SMILES CC(C(C(C1=CC=C(Cl)C=C1)=N[C@@H](CC(NCCOCCCOCC(N[C@@H](C(C)(C)C)C(N(C[C@H](O)C2)[C@@H]2C(N[C@H](C3=CC=C(C(SC=N4)=C4C)C=C3)C)=O)=O)=O)=O)C5=NN=C(C)N65)=C6S7)=C7C
Molecular Weight (g/mol) 986.64
Formula Weight 986.64
Percent Purity 96.75%
Grade Research
Physical Form Solid
For Use With (Application) Cancer-programmed cell death
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Research purposes only

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