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ARFGAP1 Mouse anti-Human, Clone: OTI1H4, lyophilized, TrueMAB™
Mouse Monoclonal Antibody
Brand: Origene Technologies CF502594
This item is not returnable.
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Description
Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO
ArfGAP1 is a 406 amino acid containing regulatory protein with an Arf-GAP domain known to be involved in the activation of the GTPase activity of ADP ribosylation factor (ARF). ArfGAP1, a GTPase-activating protein (GAP) for the ADP ribosylation factor 1 (ARF1), promotes the hydrolysis of ARF1-bound GTP and is required for the dissociation of coat proteins from Golgi-derived membranes and vesicles thus playing an important role in membrane trafficking and/or vesicle transport. Dissociation of the coat proteins is required for the fusion of these vesicles with target compartments. The activity of this protein is stimulated by phosphoinosides and inhibited by phosphatidylcholine. Two transcript variants encoding different isoforms have been reported. Ubiquitous expression of ArfGAP1 is seen in most tissues.Specifications
| ARFGAP1 | |
| Monoclonal | |
| Unconjugated | |
| ARFGAP1 | |
| ARF1GAP, HRIHFB2281 | |
| Mouse | |
| Affinity Chromatography | |
| RUO | |
| 55738 | |
| -20° C, Avoid Freeze/Thaw Cycles | |
| Lyophilized |
| Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot | |
| OTI1H4 | |
| PBS with 8% trehalose and no preservative; pH 7.3 | |
| Q8N6T3 | |
| ARFGAP1 | |
| Full length human recombit protein of human ARFGAP1 produced in HEK293T cell. | |
| 100 μg | |
| Primary | |
| Human | |
| Antibody | |
| IgG2b |
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