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Phospho-Fyn (Tyr530) Polyclonal Antibody, Invitrogen™

Product Code. 15565041
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Quantity:
100 μg
Unit Size:
100µg
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15565041 100 μg 100µg
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Product Code. 15565041 Supplier Invitrogen Supplier No. PA538115

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Description

Rabbit Polyclonal Antibody

Fyn is a membrane-associated, non-receptor protein tyrosine kinase approximately 59kDa, which belongs to the Src family of cytoplasmic tyrosine kinases. Fyn is very strongly similar to mouse Fyn, v-yes and c-src. Fyn is expressed predominately in tissues of neuronal and hematopoietic origin. Neuronal Fyn and hematopoietic Fyn differ at the junction of the SH2 and kinase domains due to tissue specific alternative splicing. Fyn has been shown to be involved in B cell and T cell activation as well as keratinocyte differentiation. In T cells, Fyn associates with the T-cell antigen receptor and Thy1.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Phospho-Fyn (Tyr530)
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation Dulbecco′s PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide; pH 7.4
Gene FYN
Gene Accession No. P06241, P39688
Gene Alias EC 2.7.10.2, FYN, P59-FYN, SLK, SYN, kinase Fyn
Gene Symbols FYN
Host Species Rabbit
Immunogen A synthetic phosphopeptide derived from human Fyn around the phosphorylation site of Tyr530 (P-Q-YP-Q-P)
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 14360, 2534
Target Species Human, Mouse
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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