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LRP Mouse, Unlabeled, Clone: 42, BD

Product Code. 15845499
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Quantity:
50 μg
Unit Size:
1 set
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15845499 50 μg 1 set
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Product Code. 15845499 Supplier BD Biosciences Supplier No. 610512

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Description

Mouse Monoclonal Antibody

Drugs that selectively attack dividing cells are often used in cancer therapy. However, small cell populations do not die, but develop resistance to a variety of toxic drugs. Multidrug resistance is achieved by gene amplification of specific membrane-bound transport ATPases that shuttle the drugs out of cells. Some multidrug-resistant cancer cells express a protein of 110 kDa named LRP (Lung Resistance-related Protein). LRP expression might be an indicator of prognosis after chemotherapy in acute myeloid leukemia and ovarian carcinoma. The LRP gene encodes a protein of 896 amino acids with significant homology to the major vault protein from Dictyostelium discoideum. Although ubiquitously expressed, LRP is most abundant in epithelial cells.

TRUSTED_SUSTAINABILITY

Specifications

Antigen LRP
Applications Immunohistochemistry, Immunoprecipitation, Western Blot
Classification Monoclonal
Clone 42
Concentration 250μg/mL
Conjugate Unconjugated
Formulation Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Host Species Mouse
Immunogen Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Purification Method Affinity Purified
Quantity 50 μg
Regulatory Status RUO
Research Discipline Cell Biology
Primary or Secondary Primary
Target Species Bovine, Canine, Human, Rabbit
Content And Storage Store undiluted at -20°C.
Isotype IgG1
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