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Invitrogen™ KSHV ORF8 Polyclonal Antibody
Rabbit Polyclonal Antibody
Brand: Invitrogen™ PA519852
This item is not returnable.
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Description
PA5-19852 targets KSHV ORF8 in indirect ELISA, WB applications and shows reactivity with Human samples. The PA5-19852 immunogen is synthetic peptide, corresponding to amino acids sequence of KSHV ORF8. .
Kaposi's sarcoma-associated herpesvirus (KSHV) belongs to the gamma-(2)-herpesvirus subfamily and has been closely linked to the Kaposi's sarcoma, primary effusion lymphoma (PEL) and multicentric Castleman's disease. The genome of KSHV is 165-170 kb and contains at least 88 open reading frames. KSHV ORF8 is a virion envelope-associated protein. Akula et al (2003) report it acts as a Glycoprotein B mediated signaling during virus entry. This Glycoprotein possesses the Arg-Gly-Asp (RGD) motif and utilizes alpha3beta1 integrin as one of the receptors for its entry into the target cells.
Specifications
| KSHV ORF8 | |
| Polyclonal | |
| Unconjugated | |
| Kaposi's Sarcoma Virus; Kaposi's sarcoma-associated herpesvirus | |
| Synthetic peptide, corresponding to amino acids sequence of KSHV ORF8. | |
| RUO | |
| Virus | |
| Antibody | |
| IgG |
| ELISA, Western Blot | |
| Conc. Not Determined | |
| whole serum with no preservative | |
| Rabbit | |
| 100 μL | |
| Primary | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
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