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Invitrogen™ Kininogen 1 Monoclonal Antibody (288422)

Rat Monoclonal Antibody

Brand:  Invitrogen™ MA523988

Product Code. 15513682

  • 457.00 EUR / 100µg

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Description

Description

In Western blots, reacts with the full length mouse Kininogen (aa 21-661), but not with the light chain alone. In Western blots, no cross-reactivity with recombinant human (rh) Cystatin D, F, SA, SN, recombinant mouse (rm) Cystatin A, B, C, E/M, rmCystatin/Stefin Homolog, rmFetuin A, rhFetuin B, rmHPRG, rhKininogen, or rhKininostatin is observed. Reconstitute at 0.5 mg/mL in sterile PBS.

This gene uses alternative splicing to generate two different proteins- high molecular weight kininogen (HMWK) and low molecular weight kininogen (LMWK). HMWK is essential for blood coagulation and assembly of the kallikrein-kinin system. Also, bradykinin, a peptide causing numerous physiological effects, is released from HMWK. In contrast to HMWK, LMWK is not involved in blood coagulation. Three transcript variants encoding different isoforms have been found for this gene.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

Kininogen 1
Monoclonal
0.5 mg/mL
PBS with 5% trehalose and No Preservative
O08677
KNG1
Mouse myeloma cell line NS0-derived recombinant mouse Kininogen Glu21-Ser661.
100 μg
Primary
Mouse
Antibody
IgG2a
Immunoprecipitation, Western Blot
288422
Unconjugated
KNG1
alpha-1-MAP; Alpha-2-thiol proteinase inhibitor; BDK; BK; Bradykinin; fitzgerald factor; high molecular weight kininogen; H-kininigen; HMWK; Ile-Ser-Bradykinin; Kallidin I; Kallidin II; kininogen; kininogen 1; kininogen 1-like 1; kininogen-1; Kininogen-1 heavy chain; Kininogen-1 light chain; Kng; Kng1; Kng1l1; L-kininogen; low molecular weight (LMW) T-kininogen II; Low molecular weight growth-promoting factor; Lysyl-bradykinin; Major acute phase protein; major acute phase protein (alpha-1-MAP); Thiostatin; T-kinin; T-kininogen 2; T-kininogen 2 heavy chain; T-kininogen 2 light chain; T-kininogen II; T-kininogen II heavy chain; T-kininogen II light chain; williams-Fitzgerald-Flaujeac factor
Rat
Protein A/G
RUO
16644
-20°C, Avoid Freeze/Thaw Cycles
Lyophilized
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