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hydroxysteroid (11-beta) dehydrogenase 1, Mouse, Clone: 2C10, Abnova™
Mouse monoclonal antibody raised against a full-length recombinant HSD11B1.
Brand: Abnova H00003290-M02A.200uL
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Description
The protein encoded by this gene is a microsomal enzyme that catalyzes the conversion of the stress hormone cortisol to the inactive metabolite cortisone. In addition, the encoded protein can catalyze the reverse reaction, the conversion of cortisone to cortisol. Too much cortisol can lead to central obesity, and a particular variation in this gene has been associated with obesity and insulin resistance in children. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq
Sequence: MAFMKKYLLPILGLFMAYYYYSANEEFRPEMLQGKKVIVTGASKGIGREMAYHLAKMGAHVVVTARSKETLQKVVSHCLELGAASAHYIAGTMEDMTFAEQFVAQAGKLMGGLDMLILNHITNTSLNLFHDDIHHVRKSMEVNFLSYVVLTVAALPMLKQSNGSIVVVSSLAGKVAYPMVAAYSASKFALDGFFSSIRKEYSVSRVNVSITLCVLGLIDTETAMKAVSGIVHMQAAPKEECALEIIKGGALRQEEVYYDSSLWTTLLIRNPCRKILEFLYSTSYNMDRFINKSpecifications
| hydroxysteroid (11-beta) dehydrogenase 1 | |
| Monoclonal | |
| Unconjugated | |
| ascites with no preservative | |
| BC012593 | |
| HSD11B1 | |
| HSD11B1 (AAH12593, 1 a.a. ∼ 292 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. | |
| RUO | |
| Primary | |
| Human | |
| Antibody | |
| IgM κ |
| ELISA, Western Blot | |
| 2C10 | |
| Mouse monoclonal antibody raised against a full length recombinant HSD11B1. | |
| HSD11B1 | |
| 11-DH/11-beta-HSD1/HDL/HSD11/HSD11B/HSD11L/MGC13539/SDR26C1 | |
| Mouse | |
| 200 μL | |
| Yes | |
| 3290 | |
| Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. | |
| Ascites |
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