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DUSP5 (M04), Mouse anti-Human, Clone: 2F3, Abnova™

Mouse monoclonal antibody raised against a partial recombinant DUSP5.

Brand:  Abnova H00001847-M04.100ug

Product Code. 16127384

  • 356.00 EUR / 100µg

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Description

Description

The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product inactivates ERK1, is expressed in a variety of tissues with the highest levels in pancreas and brain, and is localized in the nucleus. [provided by RefSeq

Sequence: LKEAFDYIKQRRSMVSPNFGFMGQLLQYESEILPSTPNPQPPSCQGEAAGSSLIGHLQTLSPDMQGAYCTFPASVLAPVPTHSTVSELSRSPVATATSC
Specifications

Specifications

DUSP5
Monoclonal
Unconjugated
PBS with no preservative; pH 7.4
NM_004419
DUSP5
DUSP5 (NP_004410, 286 a.a. ∼ 384 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
100 μg
Primary
Human, Rat
Antibody
IgG2b κ
ELISA, Immunofluorescence, Western Blot
2F3
Mouse monoclonal antibody raised against a partial recombinant DUSP5.
DUSP5
DUSP/HVH3
Mouse
Affinity chromatography
RUO
1847
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Liquid
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