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CD247 with control Mouse anti-Human, Unlabeled, Clone: 8D3, BD
Mouse Monoclonal Antibody
216.57 EUR - 387.65 EUR
Specifications
| Antigen | CD247 with control |
|---|---|
| Clone | 8D3 |
| Applications | Western Blot |
| Classification | Monoclonal |
| Conjugate | Unconjugated |
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|---|---|---|---|---|---|---|---|---|---|
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|
15806488
|
BD Biosciences
551033 |
50 μg |
 217.00 EUR 216.57 EUR / Each Save 0.43 EUR 0.20% Off |
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|
15816488
|
BD Biosciences
551034 |
150 μg |
429.00 EUR 387.65 EUR / Each Save 41.35 EUR 9% Off |
Please sign in to purchase this item. Need a web account? Register with us today! | |||||
Description
The T-cell receptor (TCR), expressed by thymus-derived lymphocytes, is a multi-component complex responsible for recognizing antigen in the context of MHC molecules. Ti is the antigen-specific binding component of the TCR. On the majority of peripheral T lymphocytes Ti is present as a disulfide-linked α - β heterodimer. A minor fraction express Ti as a γ- δ heterodimer. The Ti subunits are Ig-like, each containing V and C regions. Ti is noncovalently associated with an invariant set of molecules referred to as the CD3 subunits. CD3 appears early in thymocyte differentiation and remains expressed on all mature T lymphocytes. In the mouse, it consists of five chains, γ(gamma), δ (delta), ε (epsilon), ζ (zeta), and p21. The relative masses of the mouse CD3 chains are 21, 28, 26, 32 (dimer), and 21 kDa respectively.
The 8D3 antibody recognizes the ζ chain of the human and mouse T cell antigen receptor-associated CD3 complex. It reacts with 16 kDa unphosphorylated monomers and 32 kDa unphosphorylated dimers. It does not appear to recognize 21 kDa phosphorylated monomers or 42 kDa phosphorylated dimers. A synthetic peptide corresponding to a region of human CD3 ζ was used as immunogen.
Specifications
| CD247 with control | |
| Western Blot | |
| Unconjugated | |
| RUO | |
| IgG1 | |
| Affinity Purified | |
| CD3ζ chain |
| 8D3 | |
| Monoclonal | |
| Mouse | |
| Human, Mouse | |
| Primary | |
| Store undiluted at -20°C. |
For Research Use Only.
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