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Amphiregulin Monoclonal Antibody (AREG559), eBioscience™, Invitrogen™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 14-5370-95

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Product Code. 17170662

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Description

Description

The AREG858 monoclonal antibody reacts with human Amphiregulin (AR). AR is a member of the Epidermal Growth Factor (EGF) family and is expressed as a transmembrane precursor protein and released by proteolytic cleavage. Soluble AR is a ligand for the EGF receptor (EGFR) and the interaction promotes growth of normal epithelial cells, fibroblasts and keratinocytes. In the context of the immune system AR functions as an effector molecule for tissue repair and homeostasis, mediates resistance and tolerance to infection, and suppresses inflammation. Under different disease and activating conditions AR is expressed in T cells, group 2 innate lymphoid cells, basophils, mast cells, eosinophils, and neutrophils. Applications Reported: This AREG559 antibody has been reported for use in flow cytometric analysis and western blot. Applications Tested: This AREG559 antibody has been tested by western blot analysis of stimulated normal human peripheral blood cells. This can be used 1-10 μg/mL. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest.

Amphiregulin Monoclonal antibody specifically detects Amphiregulin in Human samples. It is validated for Flow Cytometry, Western Blot
TRUSTED_SUSTAINABILITY
Specifications

Specifications

Amphiregulin
Monoclonal
0.5 mg/mL
PBS with 0.09% sodium azide; pH 7.2
P15514
Mouse
10 mg
Primary
Human
Antibody
IgG1 κ
Flow Cytometry, Western Blot
AREG559
Unconjugated
AREG
amphiregulin; amphiregulin B; AR; AREG; AREGB; Colorectum cell-derived growth factor; CRDGF; Mcub; MGC13647; schwannoma-derived growth factor; Sdgf
Affinity chromatography
RUO
374
4° C, do not freeze
Liquid
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