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Invitrogen™ alpha Adducin Polyclonal Antibody
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Product Code. 16528011
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Quantity:
100 μL
Unit Size:
100µL
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Product Code. Quantity unitSize
16528011 100 μL 100µL
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Product Code. 16528011 Supplier Invitrogen™ Supplier No. PA590820

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Description

Rabbit Polyclonal Antibody

Immunogen sequence: MILQSPAFCE ELESMIQEQF KKGKNPTGLL ALQQIADFMT TNVPNVYPAA PQGGMAALNM SLGMVTPVND LRGSDSIAYD KGEKLLRCKL AAFYRLADLF GWSQLIYNHI TTRVNSEQEH FLIVPFGLLY SEVTASSLVK INLQGDIVDR GSTNLGVNQA GFTLHSAIYA ARPDVKCVVH IHTPAGAAVS AMKCGLLPIS PEALSLGEVA YHDYHGILVD EEEKVLIQKN LGPKSKVLIL R; Positive Samples: BT-474, Mouse brain; Cellular Location: Cell membrane, Cytoplasm, Cytoplasmic side, Peripheral membrane protein, cytoskeleton.

Adducins are a family of cytoskeleton proteins encoded by three genes (alpha, beta, gamma). Adducin is a heterodimeric protein that consists of related subunits, which are produced from distinct genes but share a similar structure. Alpha- and beta-adducin include a protease-resistant N-terminal region and a protease-sensitive, hydrophilic C-terminal region. Alpha- and gamma-adducins are ubiquitously expressed. In contrast, beta-adducin is expressed at high levels in brain and hematopoietic tissues. Adducin binds with high affinity to Ca(2+)/calmodulin and is a substrate for protein kinases A and C. Alternative splicing results in multiple variants encoding distinct isoforms; however, not all variants have been fully described.
TRUSTED_SUSTAINABILITY

Specifications

Antigen alpha Adducin
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 0.78 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene ADD1
Gene Accession No. P35611, Q9QYC0
Gene Alias Add1; ADD2; ADDA; ADDB; adducin 1; adducin 1 (alpha); Adducin beta; Adducin1; Adducin-1; Adducin-alpha; Adducin-beta; AI256389; Alpha adducin; alpha-ADD; alpha-adducin; beta Adducin; Beta-adducin; erythrocyte adducin alpha subunit; erythrocyte adducin subunit alpha
Gene Symbols ADD1
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 60-300 of human ADD1 (NP_0549082).
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 11518, 118
Target Species Human, Mouse
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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