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Invitrogen™ 90K/Mac-2BP Monoclonal Antibody (SP-2), eBioscience™
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Product Code. 15511437
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Quantity:
100 μg
Unit Size:
100µg
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15511437 100 μg 100µg
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Product Code. 15511437 Supplier Invitrogen™ Supplier No. BMS146

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Description

Mouse Monoclonal Antibody

Description: BMS146 specifically recognizes Mac-2 (galectin-3) mucin-like binding domain of human 90K/Mac-2BP. Mac-2BP is a highly glycosylated protein that plays a major role in cancer research. Elevated levels in sera have been found in many patients suffering from various types of cancer or viral infections. Applications Tested: Immunohistochemistry (Paraffin), Western Blotting. Purity: >95%.

The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. LGALS3BP has been found elevated in the serum of patients with cancer and in those infected by the human immunodeficiency virus (HIV). It appears to be implicated in immune response associated with natural killer (NK) and lymphokine-activated killer (LAK) cell cytotoxicity. Using fluorescence in situ hybridization the full length 90K cDNA has been localized to chromosome 17q25. The native protein binds specifically to a human macrophage-associated lectin known as Mac-2 and also binds galectin 1.
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Specifications

Antigen 90K/Mac-2BP
Applications Immunohistochemistry, Western Blot
Classification Monoclonal
Clone SP-2
Concentration 0.1 mg/mL
Conjugate Unconjugated
Formulation PBS with no preservative; pH 7.2-7.4
Gene LGALS3BP
Gene Accession No. Q08380
Gene Alias 90K; basement membrane autoantigen p105; BTBD17B; CyCAP; Cyp-C-associated protein; galectin 3 binding protein; galectin-3-binding protein; gp90; L3 antigen; Lectin; lectin galactoside-binding soluble 3 binding protein; lectin galactoside-binding soluble 3-binding protein; lectin, galactoside binding soluble 3 binding protein; lectin, galactoside-binding, soluble, 3 binding protein; Lgals3bp; M2BP; mac-2 BP; mac-2-binding protein; MAC2BP; MAC-2BP; MAC-2-BP; mama; peptidylprolyl isomerase C-associated protein; Ppicap; Protein 90K; Protein MAMA; serum protein 90K; similar to Galectin-3 binding protein precursor (Lectin galactoside-binding soluble 3 binding protein) (Mac-2 binding protein) (Mac-2 BP) (MAC2BP) (Tumor-associated antigen 90K); TANGO10B; transport and golgi organization 10 homolog B; tumor-associated antigen 90K
Gene Symbols LGALS3BP
Host Species Mouse
Immunogen Rec. Human Mac-2BP.
Purification Method Affinity Chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3959
Target Species Human
Content And Storage 4°C
Product Type Antibody
Form Liquid
Isotype IgG1
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