CAS RN 2097002-61-2

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MedChemExpress Selitrectinib (LOXO-195) is a next-generation TRK kinase inhibitor, with IC50s of 0.6 nM and TRKA and TRKC, respectively.

Molecular Weight (g/mol)	380.42
Color	Off-White
Physical Form	Solid
Chemical Name or Material	Selitrectinib
Grade	Research
SMILES	FC1=CN=C(CC[C@H](N2)C)C([C@](CCC3)([H])N3C(C=CN4N=C5)=NC4=C5C2=O)=C1
For Use With (Application)	Cancer-Kinase/protease
Percent Purity	98.06%
CAS	2097002-61-2
Solubility Information	DMSO : 62.5 mg/mL (164.29 mM; Need ultrasonic)
Synonym	LOXO-195
Purity Grade Notes	Research
Recommended Storage	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula	C₂₀H₂₁FN₆O
Formula Weight	380.42