CAS RN 1622902-68-4

IUPAC Name: —

Synonyms: —

Molecular Weight (g/mol): —

Molecular Formula: —

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Grade

Molecular Weight (g/mol)

Percent Purity

Physical Form

Quantity

MedChemExpress Abrocitinib (PF-04965842) is a potent, orally active and selective JAK1 inhibitor, with IC50s of 29 and 803 nM for JAK1 and JAK2, respectively. Abrocitinib (PF-04965842) exhibits less active effect on TYK2 (IC50, 1.253 μM), and inhibits phosphorylation of STAT1, STAT3 and STAT5 after stimulation. Effective in autoimmune disease.

Pricing and Availability
Specifications

Molecular Weight (g/mol)	323.41
Color	Yellow
Physical Form	Solid
Chemical Name or Material	Abrocitinib
Grade	Research
SMILES	CN([C@H]1C[C@@H](NS(CCC)(=O)=O)C1)C2=C3C(NC=C3)=NC=N2
For Use With (Application)	COVID-19-immunoregulation
Percent Purity	99.04%
CAS	1622902-68-4
Solubility Information	DMSO : 125 mg/mL (386.51 mM; Need ultrasonic)
Health Hazard 1	H302
Synonym	PF-04965842
Purity Grade Notes	Research
Recommended Storage	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula	C₁₄H₂₁N₅O₂S
Formula Weight	323.41

CAS RN 1622902-68-4

CAS RN 1622902-68-4

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