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Benzophenones

Organic compounds that contain two benzene rings fused by a ketone and have the following structure: (C6H5)2CO; commonly, carbons in the aromatic rings will have functional group substitutions.
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Keyword Search:
1 – 4 of 4 results
1

Danthron, MedChemExpress

MedChemExpress Danthron is a natural product extracted from the traditional Chinese medicine rhubarb. Danthron functions in regulating glucose and lipid metabolism by activating AMPK.

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2

Oxybenzone, MedChemExpress

MedChemExpress Oxybenzone (Benzophenone 3) is a commonly used UV filter in sun tans and skin protectants. Oxybenzone act as endocrine disrupting chemicals (EDCs) and can pass through the placental and blood-brain barriers. Benzophenone-3 impairs autophagy, alters epigenetic status, and disrupts retinoid X receptor signaling in apoptotic neuronal cells.

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3

Elacridar hydrochloride, MedChemExpress

MedChemExpress Elacridar hydrochloride (GF120918A) is an orally active P-glycoprotein (P-gp) and breast cancer resistance protein (BCRP) inhibitor. Elacridar hydrochloride can be used to examine the influence of efflux transporters on drug distribution to brain and it can be used for the research of cancer.

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Molecular Weight (g/mol) 600.1
Color Yellow
Physical Form Solid
Chemical Name or Material Elacridar hydrochloride
Grade Research
SMILES O=C1C2=CC=CC(C(NC(C=C3)=CC=C3CCN4CC(C=C(C(OC)=C5)OC)=C5CC4)=O)=C2NC6=C1C=CC=C6OC.[H]Cl
For Use With (Application) Cancer-programmed cell death
Percent Purity 98.87%
CAS 143851-98-3
Solubility Information DMSO : 62.5 mg/mL (104.15 mM; Need ultrasonic) ∣H2O : < 0.1 mg/mL (ultrasonic;warming;heat to 60°C) (insoluble)
Synonym GF120918A
Purity Grade Notes Research
Recommended Storage 4°C, sealed storage, away from moisture∣In solvent : -80°C, 6 months∣-20°C, 1 month (sealed storage, away from moisture)
Shelf Life 4°C, sealed storage, away from moisture∣In solvent : -80°C, 6 months∣-20°C, 1 month (sealed storage, away from moisture)
Molecular Formula C34H34ClN3O5
Formula Weight 600.1
4

R162, MedChemExpress

MedChemExpress R162 is a potent inhibitor of glutamate dehydrogenase 1 (GDH1/GLUD1), with anti-cancer properties.

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Molecular Weight (g/mol) 264.28
Color Yellow
Physical Form Solid
Chemical Name or Material R162
Grade Research
SMILES O=C1C2=C(C=CC=C2)C(C3=CC=C(CC=C)C(O)=C13)=O
For Use With (Application) Cancer-programmed cell death
Percent Purity 98.04%
CAS 64302-87-0
Solubility Information DMF : 6.25 mg/mL (23.65 mM; ultrasonic and warming and heat to 60°C) ∣DMSO : 5.2 mg/mL (19.68 mM; Need ultrasonic) ∣Ethanol : 2 mg/mL (7.57 mM; Need ultrasonic) ∣H2O : < 0.1 mg/mL (ultrasonic) (insoluble)
Purity Grade Notes Research
Recommended Storage Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula C17H12O3
Formula Weight 264.28